People sometimes ask, what is the difference between catching System.Exception and the General Exception in a Catch Exception shape in the orchestration designer in BizTalk.
Off course, an obvious difference is, that with the General Exception, you don't get an object with properties to investigate. But then it seems that the General Exception is useless... surely there is a point to it?
Well, I was curious about this myself, so I investigated a bit, and found this post. So basically, I think the catch of the general exception in BizTalk 2006 is a left over from BizTalk 2004. In BizTalk 2004 it made sense, since you actually have exceptions thrown at you that didn't derive from System.Exception. That is no longer possible in .NET 2.0 - they just haven't removed it from the designer - probably just to be backwards compatible.