Hi
I just thought I would share my experiences from the first BizTalk 2006 R2 I have installed and configured.
It was on two different boxes - one for SQL Server and one for BizTalk. Domain groups were created beforehand, as well as a service account for the services. So everything should be in place.
Installation went fine, naturally, but the configuration wouldn't let me configure Group and Runtime. I checked the logs, off course, and the first error was this one:
[09:14:15 Info ConfigHelper] is not a local entity.
[09:14:15 Error ConfigHelper] d:\depot2300\mercury\private\common\configwizard\confighelper\service.cpp(729): FAILED hr = 80070421
[09:14:15 Warning ConfigHelper] The account name is invalid or does not exist, or the password is invalid for the account name specified.
[09:14:15 Warning ConfigHelper] Failed to validate service credentials for account: %1
So it had to be something about the credentials I have specified. So I unconfigured, reconfigured, being very carefully to enter the correct credentials - same error. I tried again, with extra extra focus on not mistyping anything. Same error.
Then I searched some more in the log file, and found this:
2007-09-25 09:16:49:0441 [INFO] WMI Deploying 'C:\Program Files\Microsoft BizTalk Server 2006\Microsoft.BizTalk.GlobalPropertySchemas.dll'
2007-09-25 09:16:49:0723 [WARN] AdminLib GetBTSMessage: hrErr=80070002; Msg=The system cannot find the file specified.;
2007-09-25 09:16:49:0723 [WARN] AdminLib GetBTSMessage: hrErr=c0c02560; Msg=Failed to read "KeepDbDebugKey" from the registry.
The system cannot find the file specified.;
But the file actually existed. Then I searched the log file some more, and found this:
2007-09-25 09:16:49:0863 [INFO] WMI Error occurred during database creation; attempt to rollback and delete the partially created database'hcpr-hd-axa-01\BizTalkMgmtDb'
2007-09-25 09:16:49:0863 [INFO] WMI Calling CDataSource.Open() against hcpr-hd-axa-01\master
2007-09-25 09:16:49:0879 [INFO] WMI CDataSource.Open() returned
2007-09-25 09:17:09:0942 [WARN] WMI Rollback failed. Could not delete database.
2007-09-25 09:17:09:0942 [ERR] WMI Failed in pAdmInst->Create() in CWMIInstProv::PutInstance(). HR=c0c025b3
2007-09-25 09:17:09:0942 [ERR] WMI WMI error description is generated: Exception of type 'System.EnterpriseServices.TransactionProxyException' was thrown.
2007-09-25 09:17:09:0942 [INFO] WMI CWMIInstProv::PutInstance() finished. HR=c0c025b3
[09:17:09 Error BtsCfg] d:\depot2300\mercury\private\mozart\source\setup\btscfg\btswmi.cpp(358): FAILED hr = c0c025b3
[09:17:09 Error BtsCfg] Exception of type 'System.EnterpriseServices.TransactionProxyException' was thrown.
[09:17:09 Error BtsCfg] d:\depot2300\mercury\private\mozart\source\setup\btscfg\btscfg.cpp(1769): FAILED hr = c0c025b3
This error pointed to some transaction error, so I downloaded and ran dtctester and it turned out my MSDTC settigns were not good enough. I spend the better part of a day looking for this. What really had me confused was that the SSODB was created fine - the BRE-DB was created fine... and the BizTalkMgmtDb database was sometimes created just fine. I mean... sometimes it would create the BizTalkMgmtDB database and fail during creation of the MessageBox. Other times it would fail on the Management database. So seing as two databases were created just fine, I really didn't think there were any issues with DTC.
BUT, this just goes to show; Before starting a multibox installation of BizTalk, ALWAYS run dtc tester first - just to be sure 
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eliasen